Endocrine Abstracts

Case history: We have previously presented the case of a 31 year lady presenting with a seizure following exercise with a blood sugar of 1.4 mmol/l on a background of an 8 month history of episodic slurred speech, blurred vision and hunger relieved by eating in 2011.Investigations: Investigations confirmed an insulinoma and imaging, including Ga68 DOTATATE PET CT identified a lesion in the tail of the pancreas with multiple liver metastases. M...

Background: Paragangliomas are rare neuroendocrine tumours arising in the autonomic nervous system, which can secrete excess catecholamines, causing cardiovascular complications. Malignancy occurs in up to 23% of paragangliomas, resulting in a poor prognosis with a 5-year mortality of 43–63%. There’s a limited evidence base for their treatment, with no official guidelines. Peptide Receptor Radionuclide Therapy (PRRT) is a proven treatment for neuroendocrine tumours o...